Journal of Clinical Case Reports Medical Images and Health Sciences

Temporal loss of efficacy of monoclonal CGRPantibody treatment following an infection with SARS-CoV-2: A case report by Hesham Hegazi in Journal of Clinical Case Reports Medical Images and Health Sciences Abstract Keywords : SARS-CoV-2, fremanezumab, CGRP, monoclonal antibody, COVID-19, migraine Increase of migraine frequency or pain intensity triggered by viral infections is common, in some patients a migraine status may be a consequence (1). In most patients migraine decreases after complete resolution of the infection and the course of disease reaches previous state. Due to the pandemic situation of SARS-CoV-2 patients switching from episodic to chronic migraine frequency are reported in close temporal relation to a COVID-19 disease (2). Until now there is one case published reporting decrease of efficacy of treatment with the monoclonal CGRP (calcitonin gene-related peptide)-receptor antibody erenumab in a migraine patient previously suffering from episodic migraine. Improvement ...

The Impact of Covid-19 vaccinations on the wellbeing of doctors Worldwide by Hesham Hegazi in Journal of Clinical Case Reports Medical Images and Health Sciences Abstract Objectives : Personal-wellbeing among healthcare personnel is a complex matter. This study was conducted to evaluate the impact of Covid-19 vaccination on the personal well-being of doctors. Setting : We shared the survey with doctors on FacMedicine.com. Participants : We analyzed the data of 1679 doctors from different countries who completed the published questionnaire. The collected data included age, gender, continent, country income, specialty, career level, and the number of working hours. Results : Age distribution had no significant impact on PWS (p= 0.583). Nevertheless, the same score showed a significant rise in the males compared to females. Specialty, working hours, and continent distribution did not show a significant association with the same score. Higher medical career levels were associated with h...

  Gram-negative Cellulitis in an Immunocompromised Covid-19 Positive Patient in Anand Dhaliwal by Journal of Clinical Case Reports Medical Images and Health Sciences  Abstract Cellulitis is a commonly presenting acute bacterial infection of dermal and subcutaneous tissue, which typically presents as a warm, erythematous, and poorly demarcated area with tenderness to palpation and associated edema. Cellulitis typically is caused by Streptococcus pyogenes or Staphylococcus aureus, but as seen in this case cellulitis can be due to an underlying Escherichia coli infection. It is vital for clinicians to take a detailed history and perform a thorough physical exam when diagnosing cellulitis, as several inflammatory and neoplastic diseases present similarly. Though the use of blood cultures or needle aspirations in the diagnosis of the underlying bacteria involved in cellulitis is usually inconclusive, it is imperative that clinicians properly assess symptoms necessitating their us...